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PNA interference mapping demonstrates functional domains in the noncoding RNA Xist

The noncoding RNA Xist has been shown to be essential for X-chromosome inactivation and to coat the inactive X-chromosome (Xi). Thus, an important question in understanding the formation of Xi is whether the binding reaction of Xist is necessary for X-chromosome inactivation. In this article, we dem...

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Main Authors: Beletskii, Anton, Hong, Young-Kwon, Pehrson, John, Egholm, Michael, Strauss, William M.
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC55400/
https://ncbi.nlm.nih.gov/pubmed/11481485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161173098
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