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Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism
Aerobic glycolysis (the Warburg effect) is a metabolic hallmark of activated T cells, and has been implicated in augmenting effector T cell responses including expression of the pro-inflammatory cytokine interferon (IFN)-γ via 3′ untranslated region (3′UTR)-mediated mechanisms. Here we show that lac...
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| Publicado no: | Science |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5539971/ https://ncbi.nlm.nih.gov/pubmed/27708054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf6284 |
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