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Label-free luminescence switch-on detection of hepatitis C virus NS3 helicase activity using a G-quadruplex-selective probe

A series of luminescent Ir(iii) complexes were synthesised and evaluated for their ability to act as luminescent G-quadruplex-selective probes. The Ir(iii) complex 9, [Ir(phq)(2)(phen)]PF(6) (where phq = 2-phenylquinoline; phen = 1,10-phenanthroline), exhibited high luminescence in the presence of G...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Leung, Ka-Ho, He, Hong-Zhang, He, Bingyong, Zhong, Hai-Jing, Lin, Sheng, Wang, Yi-Tao, Ma, Dik-Lung, Leung, Chung-Hang
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539802/
https://ncbi.nlm.nih.gov/pubmed/28808523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4sc03319a
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