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Development of a luminescent G-quadruplex-selective iridium(III) complex for the label-free detection of adenosine

A panel of six luminescent iridium(III) complexes were synthesized and evaluated for their ability to act as G-quadruplex-selective probes. The novel iridium(III) complex 1 was found to be highly selective for G-quadruplex DNA, and was employed for the construction of a label-free G-quadruplex-based...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Lu, Lihua, Zhong, Hai-Jing, He, Bingyong, Leung, Chung-Hang, Ma, Dik-Lung
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726048/
https://ncbi.nlm.nih.gov/pubmed/26778273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19368
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