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Coupling of Challenging Heteroaryl Halides with Alkyl Halides via Nickel-Catalyzed Cross-Electrophile Coupling
[Image: see text] Despite their importance, the synthesis of alkylated heterocycles from the cross-coupling of Lewis basic nitrogen heteroaryl halides with alkyl halides remains a challenge. We report here a general solution to this challenge enabled by a new collection of ligands based around 2-pyr...
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| Veröffentlicht in: | J Org Chem |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Chemical
Society
2017
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5539790/ https://ncbi.nlm.nih.gov/pubmed/28682073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b01334 |
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