Low density DNA microarray for detection of most frequent TP53 missense point mutations

BACKGROUND: We have developed an oligonucleotide microarray (genosensor) utilizing a double tandem hybridization technique to search for 9 point mutations located in the most frequently altered codons of the TP53 gene. Isolated and multiplexed PCR products, 108 and 92 bp long, from exons 7 and 8, re...

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Bibliografiske detaljer
Main Authors: Rangel-López, Angélica, Maldonado-Rodríguez, Rogelio, Salcedo-Vargas, Mauricio, Espinosa-Lara, Juana Mercedes, Méndez-Tenorio, Alfonso, Beattie, Kenneth L
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2005
Fag:
Methodology Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC553977/
https://ncbi.nlm.nih.gov/pubmed/15713227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-5-8
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