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Nickel-Catalyzed Asymmetric Kumada Cross-Coupling of Symmetric Cyclic Sulfates

Nickel-catalyzed enantioselective cross- couplings between symmetric cyclic sulfates and aromatic Grignard reagents are described. These reactions are effective with a broad range of substituted cyclic sulfates and deliver products with asymmetric tertiary carbon centers. Mechanistic experiments poi...

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Publicat a:J Am Chem Soc
Autors principals: Eno, Meredith S., Lu, Alexander, Morken, James P.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539537/
https://ncbi.nlm.nih.gov/pubmed/27276235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b03384
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