Dengue Virus-Infected Dendritic Cells, but Not Monocytes, Activate Natural Killer Cells through a Contact-Dependent Mechanism Involving Adhesion Molecules

Natural killer (NK) cells play a protective role against dengue virus (DENV) infection, but the cellular and molecular mechanisms are not fully understood. Using an optimized humanized mouse model, we show that human NK cells, through the secretion of gamma interferon (IFN-γ), are critical in the ea...

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Publicat a:mBio
Autors principals: Costa, Vivian Vasconcelos, Ye, Weijian, Chen, Qingfeng, Teixeira, Mauro Martins, Preiser, Peter, Ooi, Eng Eong, Chen, Jianzhu
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539423/
https://ncbi.nlm.nih.gov/pubmed/28765218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00741-17
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