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Inhibition of Megakaryocyte Development in the Bone Marrow Underlies Dengue Virus-Induced Thrombocytopenia in Humanized Mice

A characteristic clinical feature of dengue virus infection is thrombocytopenia, though its underlying mechanism is not definitively determined. By adoptive transfer of human CD34(+) fetal liver cells into immunodeficient mice, we have constructed humanized mice with significant levels of human plat...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sridharan, Aishwarya, Chen, Qingfeng, Tang, Kin Fai, Ooi, Eng Eong, Hibberd, Martin L., Chen, Jianzhu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807371/
https://ncbi.nlm.nih.gov/pubmed/23966397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01156-13
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