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Semaphorin 4C Plexin-B2 signaling in peripheral sensory neurons is pronociceptive in a model of inflammatory pain

Semaphorins and their transmembrane receptors, Plexins, are key regulators of axon guidance and development of neuronal connectivity. B-type Plexins respond to Class IV semaphorins and mediate a variety of developmental functions. Here we report that the expression of Plexin-B2 and its high-affinity...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Paldy, Eszter, Simonetti, Manuela, Worzfeld, Thomas, Bali, Kiran Kumar, Vicuña, Lucas, Offermanns, Stefan, Kuner, Rohini
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539317/
https://ncbi.nlm.nih.gov/pubmed/28765520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00341-w
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