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Semaphorin 4D Signaling Requires the Recruitment of Phospholipase Cγ into the Plexin-B1 Receptor Complex

The semaphorin 4D (Sema4D) receptor plexin-B1 constitutively interacts with particular Rho guanine nucleotide exchange factors (RhoGEFs) and thereby mediates Sema4D-induced RhoA activation, a process which involves the tyrosine phosphorylation of plexin-B1 by ErbB-2. It is, however, unknown how plex...

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Detalhes bibliográficos
Main Authors: Swiercz, Jakub M., Worzfeld, Thomas, Offermanns, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786695/
https://ncbi.nlm.nih.gov/pubmed/19805522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00103-09
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