Hypomethylation of CNTFRα is associated with proliferation and poor prognosis in lower grade gliomas

Ciliary neurotrophic factor receptor α subunit (CNTFRα) and CNTF play important roles in neuron survival, glial differentiation and brain tumor growth. However, the molecular mechanisms of CNTFRα regulation and its clinical significance in glioma remain largely unknown. Here, we found CNTFRα was ove...

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Publicat a:Sci Rep
Autors principals: Fan, Kun, Wang, Xiaowen, Zhang, Jingwen, Ramos, Romela Irene, Zhang, Haibo, Li, Chunjie, Ye, Dan, Kang, Jiansheng, Marzese, Diego M., Hoon, Dave S. B., Hua, Wei
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539284/
https://ncbi.nlm.nih.gov/pubmed/28765641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07124-9
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