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Pdx1-Cre-driven conditional gene depletion suggests PAK4 as dispensable for mouse pancreas development
Constitutive depletion of p21-activated kinase 4 (PAK4) in the mouse causes embryonic lethality associated with heart and brain defects. Given that conventional gene depletion of PAK1 or PAK3 caused functional deficits in the mouse pancreas, while gene depletion of PAK5 or PAK6 did not, we asked if...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5539201/ https://ncbi.nlm.nih.gov/pubmed/28765528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07322-5 |
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