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CD14 is critical for TLR2-mediated M1 macrophage activation triggered by N-glycan recognition
Agonist interaction with Toll-like receptors (TLRs) induces T cell-mediated immunity, which is effective against intracellular pathogens. Consequently, TLR agonists are being tried as immunomodulatory agents. The lectin ArtinM targets TLR2 N-glycans on macrophages, induces cytokines production, and...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5539197/ https://ncbi.nlm.nih.gov/pubmed/28765651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07397-0 |
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