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CD14 is critical for TLR2-mediated M1 macrophage activation triggered by N-glycan recognition

Agonist interaction with Toll-like receptors (TLRs) induces T cell-mediated immunity, which is effective against intracellular pathogens. Consequently, TLR agonists are being tried as immunomodulatory agents. The lectin ArtinM targets TLR2 N-glycans on macrophages, induces cytokines production, and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: da Silva, Thiago Aparecido, Zorzetto-Fernandes, André L. V., Cecílio, Nerry T., Sardinha-Silva, Aline, Fernandes, Fabrício Freitas, Roque-Barreira, Maria Cristina
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539197/
https://ncbi.nlm.nih.gov/pubmed/28765651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07397-0
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