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Severity of Alcohol Dependence is Associated with the Fatty Acid Amide Hydrolase Pro129Thr Missense Variant

The endocannabinoid system plays an important role in reward and addiction. One of the two main endocannabinoid neurotransmitters, anandamide, is metabolized by fatty acid amide hydrolase, an enzyme with a functional genetic polymorphism (FAAH Pro129Thr, rs324420). The Thr129 allele has been linked...

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Detalhes bibliográficos
Publicado no:Addict Biol
Main Authors: Sloan, Matthew E., Gowin, Joshua L., Yan, Jia, Schwandt, Melanie L., Spagnolo, Primavera A., Sun, Hui, Hodgkinson, Colin A., Goldman, David, Ramchandani, Vijay A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538894/
https://ncbi.nlm.nih.gov/pubmed/28150397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12491
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