Next generation sequencing of carcinoma of unknown primary reveals novel combinatorial strategies in a heterogeneous mutational landscape

BACKGROUND: Advanced carcinoma of unknown primary (CUP) has limited effective therapeutic options given the phenotypic and genotypic diversity. To identify future novel therapeutic strategies we conducted an exploratory analysis of next-generation sequencing (NGS) of relapsed, refractory CUP. METHOD...

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Veröffentlicht in:Oncoscience
Hauptverfasser: Subbiah, Ishwaria M., Tsimberidou, Apostolia, Subbiah, Vivek, Janku, Filip, Roy-Chowdhuri, Sinchita, Hong, David S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538848/
https://ncbi.nlm.nih.gov/pubmed/28781987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncoscience.352
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