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Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing

Understanding genetic aberrations in cancer leads to discovery of new targets for cancer therapies. The genomic landscape of hepatocellular carcinoma (HCC) has not been fully described. Therefore, patients with refractory advanced/metastatic HCC referred for experimental therapies, who had adequate...

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Autors principals: Janku, Filip, Kaseb, Ahmed O., Tsimberidou, Apostolia M., Wolff, Robert A., Kurzrock, Razelle
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102787/
https://ncbi.nlm.nih.gov/pubmed/24931142
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