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Effect of acute physiological free fatty acid elevation in the context of hyperinsulinemia on fiber type-specific IMCL accumulation

It is well described that increasing free fatty acids (FFAs) to high physiological levels reduces insulin sensitivity. In sedentary humans, intramyocellular lipid (IMCL) is inversely related to insulin sensitivity. Since muscle fiber composition affects muscle metabolism, whether FFAs induce IMCL ac...

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Detalhes bibliográficos
Publicado no:J Appl Physiol (1985)
Main Authors: Chow, Lisa S., Mashek, Douglas G., Wang, Qi, Shepherd, Sam O., Goodpaster, Bret H., Dubé, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538810/
https://ncbi.nlm.nih.gov/pubmed/28450549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00209.2017
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