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Previous radiotherapy and the clinical activity and toxicity of pembrolizumab in the treatment of non-small-cell lung cancer: a secondary analysis of the KEYNOTE-001 phase 1 trial

BACKGROUND: Preclinical studies have found radiotherapy enhances antitumour immune responses. We aimed to assess disease control and pulmonary toxicity in patients who previously received radiotherapy for non-small-cell lung cancer (NSCLC) before receiving pembrolizumab. METHODS: We assessed patient...

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Bibliografiske detaljer
Udgivet i:Lancet Oncol
Main Authors: Shaverdian, Narek, Lisberg, Aaron E, Bornazyan, Krikor, Veruttipong, Darlene, Goldman, Jonathan W, Formenti, Silvia C, Garon, Edward B, Lee, Percy
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538772/
https://ncbi.nlm.nih.gov/pubmed/28551359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(17)30380-7
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