Expression of Merkelcell polyomavirus (MCPyV) large T-antigen in Merkel cell carcinoma lymph node metastases predicts poor outcome

BACKGROUND: The aim of this study was to determine the prevalence of MCPyV in Merkel cell carcinoma (MCC) primaries versus lymph node metastasis and to evaluate possible prognostic factors. METHODS: Samples of MCC primaries and lymph node metastases were stained immunohistochemically for the MCPyV l...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Haymerle, Georg, Janik, Stefan, Fochtmann, Alexandra, Pammer, Johannes, Schachner, Helga, Nemec, Lucas, Mildner, Michael, Houben, Roland, Grasl, Matthaeus Ch., Erovic, Boban M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538748/
https://ncbi.nlm.nih.gov/pubmed/28763479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180426
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