A new in situ hybridization and immunohistochemistry with a novel antibody to detect small T-antigen expressions of Merkel cell polyomavirus (MCPyV)

BACKGROUND: Approximately 80% of Merkel cell carcinomas (MCCs) harbor Merkel cell polyomavirus (MCPyV) which monoclonally integrates into the genome and has prognostic significance. The presence or absence of MCPyV is usually diagnosed using CM2B4 immunohistochemistry (IHC) for MCPyV-large T antigen...

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Detalhes bibliográficos
Main Authors: Matsushita, Michiko, Nonaka, Daisuke, Iwasaki, Takeshi, Kuwamoto, Satoshi, Murakami, Ichiro, Kato, Masako, Nagata, Keiko, Kitamura, Yukisato, Hayashi, Kazuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Methodology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994555/
https://ncbi.nlm.nih.gov/pubmed/24649978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-1596-9-65
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