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A new in situ hybridization and immunohistochemistry with a novel antibody to detect small T-antigen expressions of Merkel cell polyomavirus (MCPyV)

BACKGROUND: Approximately 80% of Merkel cell carcinomas (MCCs) harbor Merkel cell polyomavirus (MCPyV) which monoclonally integrates into the genome and has prognostic significance. The presence or absence of MCPyV is usually diagnosed using CM2B4 immunohistochemistry (IHC) for MCPyV-large T antigen...

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Autori principali: Matsushita, Michiko, Nonaka, Daisuke, Iwasaki, Takeshi, Kuwamoto, Satoshi, Murakami, Ichiro, Kato, Masako, Nagata, Keiko, Kitamura, Yukisato, Hayashi, Kazuhiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994555/
https://ncbi.nlm.nih.gov/pubmed/24649978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-1596-9-65
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