Ancient antagonism between CELF and RBFOX families tunes mRNA splicing outcomes

Over 95% of human multi-exon genes undergo alternative splicing, a process important in normal development and often dysregulated in disease. We sought to analyze the global splicing regulatory network of CELF2 in human T cells, a well-studied splicing regulator critical to T cell development and fu...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Gazzara, Matthew R., Mallory, Michael J., Roytenberg, Renat, Lindberg, John P., Jha, Anupama, Lynch, Kristen W., Barash, Yoseph
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538552/
https://ncbi.nlm.nih.gov/pubmed/28512194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.220517.117
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