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Transcriptional regulation of the human papillomavirus-16 E6-E7 promoter by a keratinocyte-dependent enhancer, and by viral E2 trans-activator and repressor gene products: implications for cervical carcinogenesis.

The transcriptional promoter of the candidate E6-E7 transforming gene region of human papillomavirus (HPV)-16 (P97) was active in transiently transfected cervical carcinoma cells when linked to the HSV-1 tk or bacterial cat genes. Sequences 5' to P97 contain a short enhancer element responding...

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Autors principals: Cripe, T P, Haugen, T H, Turk, J P, Tabatabai, F, Schmid, P G, Dürst, M, Gissmann, L, Roman, A, Turek, L P
Format: Artigo
Idioma:Inglês
Publicat: 1987
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC553845/
https://ncbi.nlm.nih.gov/pubmed/2448139
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