GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression

The eIF4E homologous protein (4EHP) is thought to repress translation by competing with eIF4E for binding to the 5′ cap structure of specific mRNAs to which it is recruited through interactions with various proteins, including the GRB10-interacting GYF (glycine–tyrosine–phenylalanine domain) protein...

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Bibliografski detalji
Izdano u:Genes Dev
Glavni autori: Peter, Daniel, Weber, Ramona, Sandmeir, Felix, Wohlbold, Lara, Helms, Sigrun, Bawankar, Praveen, Valkov, Eugene, Igreja, Cátia, Izaurralde, Elisa
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2017
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538437/
https://ncbi.nlm.nih.gov/pubmed/28698298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.299420.117
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