GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression

The eIF4E homologous protein (4EHP) is thought to repress translation by competing with eIF4E for binding to the 5′ cap structure of specific mRNAs to which it is recruited through interactions with various proteins, including the GRB10-interacting GYF (glycine–tyrosine–phenylalanine domain) protein...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genes Dev
Prif Awduron: Peter, Daniel, Weber, Ramona, Sandmeir, Felix, Wohlbold, Lara, Helms, Sigrun, Bawankar, Praveen, Valkov, Eugene, Igreja, Cátia, Izaurralde, Elisa
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2017
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538437/
https://ncbi.nlm.nih.gov/pubmed/28698298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.299420.117
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