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From structure to mechanism—understanding initiation of DNA replication

DNA replication results in the doubling of the genome prior to cell division. This process requires the assembly of 50 or more protein factors into a replication fork. Here, we review recent structural and biochemical insights that start to explain how specific proteins recognize DNA replication ori...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Riera, Alberto, Barbon, Marta, Noguchi, Yasunori, Reuter, L. Maximilian, Schneider, Sarah, Speck, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538431/
https://ncbi.nlm.nih.gov/pubmed/28717046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.298232.117
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