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Cilia and Ciliopathies in Congenital Heart Disease

A central role for cilia in congenital heart disease (CHD) was recently identified in a large-scale mouse mutagenesis screen. Although the screen was phenotype-driven, the majority of genes recovered were cilia-related, suggesting that cilia play a central role in CHD pathogenesis. This partly refle...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Biol
Main Authors: Klena, Nikolai T., Gibbs, Brian C., Lo, Cecilia W.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538412/
https://ncbi.nlm.nih.gov/pubmed/28159874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a028266
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