Global genetic analysis in mice unveils central role for cilia in congenital heart disease

Congenital heart disease (CHD) is the most prevalent birth defect, affecting nearly 1% of live births(1), but the incidence of CHD is up to ten fold higher in human fetuses(2,3). A genetic contribution is strongly suggested by the association of CHD with chromosome abnormalities and high recurrence...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nature
Hlavní autoři: Li, You, Klena, Nikolai T., Gabriel, George C, Liu, Xiaoqin, Kim, Andrew J., Lemke, Kristi, Chen, Yu, Chatterjee, Bishwanath, Devine, William, Damerla, Rama Rao, Chang, Chien-fu, Yagi, Hisato, San Agustin, Jovenal T., Thahir, Mohamed, Anderton, Shane, Lawhead, Caroline, Vescovi, Anita, Pratt, Herbert, Morgan, Judy, Haynes, Leslie, Smith, Cynthia L., Eppig, Janan T., Reinholdt, Laura, Francis, Richard, Leatherbury, Linda, Ganapathiraju, Madhavi K., Tobita, Kimimasa, Pazour, Gregory J., Lo, Cecilia W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617540/
https://ncbi.nlm.nih.gov/pubmed/25807483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14269
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky