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Global genetic analysis in mice unveils central role for cilia in congenital heart disease
Congenital heart disease (CHD) is the most prevalent birth defect, affecting nearly 1% of live births(1), but the incidence of CHD is up to ten fold higher in human fetuses(2,3). A genetic contribution is strongly suggested by the association of CHD with chromosome abnormalities and high recurrence...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4617540/ https://ncbi.nlm.nih.gov/pubmed/25807483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14269 |
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