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Clinical Spectrum of Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic lateral sclerosis (ALS) is primarily characterized by progressive loss of motor neurons, although there is marked phenotypic heterogeneity between cases. Typical, or “classical,” ALS is associated with simultaneous upper motor neuron (UMN) and lower motor neuron (LMN) involvement at dise...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Med
Main Authors: Grad, Leslie I., Rouleau, Guy A., Ravits, John, Cashman, Neil R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538408/
https://ncbi.nlm.nih.gov/pubmed/28003278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a024117
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