ApoE influences regional white-matter axonal density loss in Alzheimer's disease

Mechanisms underlying phenotypic heterogeneity in young onset Alzheimer disease (YOAD) are poorly understood. We used diffusion tensor imaging and neurite orientation dispersion and density imaging (NODDI) with tract-based spatial statistics to investigate apolipoprotein (APOE) ε4 modulation of whit...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Slattery, Catherine F., Zhang, Jiaying, Paterson, Ross W., Foulkes, Alexander J.M., Carton, Amelia, Macpherson, Kirsty, Mancini, Laura, Thomas, David L., Modat, Marc, Toussaint, Nicolas, Cash, David M., Thornton, John S., Henley, Susie M.D., Crutch, Sebastian J., Alexander, Daniel C., Ourselin, Sebastien, Fox, Nick C., Zhang, Hui, Schott, Jonathan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538347/
https://ncbi.nlm.nih.gov/pubmed/28578156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2017.04.021
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