Dissociable effects of APOE-ε4 and β-amyloid pathology on visual working memory

Although APOE-ε4 carriers are at significantly higher risk of developing Alzheimer’s disease than non-carriers(1), controversial evidence suggests that APOE-ε4 might confer some advantages, explaining the survival of this gene (antagonistic pleiotropy)(2,3). In a population-based cohort born in one...

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Publicado no:Nat Aging
Main Authors: Lu, Kirsty, Nicholas, Jennifer M., Pertzov, Yoni, Grogan, John, Husain, Masud, Pavisic, Ivanna M., James, Sarah-Naomi, Parker, Thomas D., Lane, Christopher A., Keshavan, Ashvini, Keuss, Sarah E., Buchanan, Sarah M., Murray-Smith, Heidi, Cash, David M., Malone, Ian B., Sudre, Carole H., Coath, William, Wong, Andrew, Henley, Susie M.D., Fox, Nick C., Richards, Marcus, Schott, Jonathan M., Crutch, Sebastian J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612005/
https://ncbi.nlm.nih.gov/pubmed/34806027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s43587-021-00117-4
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