A normal genetic variation modulates synaptic MMP‐9 protein levels and the severity of schizophrenia symptoms

Matrix metalloproteinase 9 (MMP‐9) has recently emerged as a molecule that contributes to pathological synaptic plasticity in schizophrenia, but explanation of the underlying mechanisms has been missing. In the present study, we performed a phenotype‐based genetic association study (PGAS) in > 1,...

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Vydáno v:EMBO Mol Med
Hlavní autoři: Lepeta, Katarzyna, Purzycka, Katarzyna J, Pachulska‐Wieczorek, Katarzyna, Mitjans, Marina, Begemann, Martin, Vafadari, Behnam, Bijata, Krystian, Adamiak, Ryszard W, Ehrenreich, Hannelore, Dziembowska, Magdalena, Kaczmarek, Leszek
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538295/
https://ncbi.nlm.nih.gov/pubmed/28623238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201707723
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