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Cell-based, bioluminescent assay for monitoring the interaction between PCSK9 and the LDL receptor

Monitoring the expression of cell-surface receptors, their interaction with extracellular ligands, and their fate upon ligand binding is important for understanding receptor function and developing new therapies. We describe a cell-based method that utilizes bioluminescent protein complementation te...

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Dades bibliogràfiques
Publicat a:J Lipid Res
Autors principals: Duellman, Sarah J., Machleidt, Thomas, Cali, James J., Vidugiriene, Jolanta
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538273/
https://ncbi.nlm.nih.gov/pubmed/28611099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D074658
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