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gal4 transcription activator protein of yeast can function as a repressor in Escherichia coli.

The chromosomal lac operator of Escherichia coli was replaced by a 22 bp oligonucleotide containing the binding site of the yeast gal4 protein. Induction of gal4 protein synthesis in these bacteria repressed beta-galactosidase synthesis at least 30-fold. These results show that it is possible to det...

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Detalles Bibliográficos
Main Authors: Paulmier, N, Yaniv, M, von Wilcken-Bergmann, B, Müller-Hill, B
Formato: Artigo
Idioma:Inglês
Publicado: 1987
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC553814/
https://ncbi.nlm.nih.gov/pubmed/3123219
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