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eIF2α phosphorylation is required to prevent hepatocyte death and liver fibrosis in mice challenged with a high fructose diet

BACKGROUND: Dietary fructose can rapidly cause fatty liver in animals through de novo lipogenesis (DNL) and contribute to the development and severity of nonalcoholic fatty liver disease (NAFLD). In response to diverse cellular insults including endoplasmic reticulum (ER) and oxidative stress, phosp...

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Detaylı Bibliyografya
Yayımlandı:Nutr Metab (Lond)
Asıl Yazarlar: Choi, Woo-Gyun, Han, Jaeseok, Kim, Ji-Hyeon, Kim, Mi-Jeong, Park, Jae-Woo, Song, Benbo, Cha, Hee-Jeong, Choi, Hye-Seon, Chung, Hun-Taeg, Lee, In-Kyu, Park, Tae-Sik, Hatzoglou, Maria, Choi, Hueng-Sik, Yoo, Hyun Ju, Kaufman, Randal J., Back, Sung Hoon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537942/
https://ncbi.nlm.nih.gov/pubmed/28781602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12986-017-0202-6
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