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Nuclear Translocation of the EGFR family Membrane Tyrosine Kinase Receptors

Integral membrane proteins contain a hydrophobic transmembrane domain and mainly locate in the plasma membrane lipid bilayer. The receptor tyrosine kinases (RTK) of the epidermal growth factor receptor (EGFR) superfamily, including ErbB-1, ErbB-2, ErbB-3, and ErbB-4, constitute an important group of...

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Bibliographic Details
Published in:Clin Cancer Res
Main Authors: Wang, Shao-Chun, Hung, Mien-Chie
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537741/
https://ncbi.nlm.nih.gov/pubmed/19861462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-2813
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