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Cisplatin‐resistant cancer cells are sensitive to Aurora kinase A inhibition by alisertib
De novo and acquired resistance to platinum therapy such as cisplatin (CDDP) is a clinical challenge in gastric cancer treatment. Aberrant expression and activation of aurora kinase A (AURKA) and eukaryotic translation initiation factor 4E (eIF4E) are detected in several cancer types. Herein, we inv...
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Publicado no: | Mol Oncol |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley and Sons Inc.
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5537695/ https://ncbi.nlm.nih.gov/pubmed/28417568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12066 |
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