Cisplatin‐resistant cancer cells are sensitive to Aurora kinase A inhibition by alisertib

De novo and acquired resistance to platinum therapy such as cisplatin (CDDP) is a clinical challenge in gastric cancer treatment. Aberrant expression and activation of aurora kinase A (AURKA) and eukaryotic translation initiation factor 4E (eIF4E) are detected in several cancer types. Herein, we inv...

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Bibliografische gegevens
Gepubliceerd in:Mol Oncol
Hoofdauteurs: Wang, Lihong, Arras, Janet, Katsha, Ahmed, Hamdan, Saif, Belkhiri, Abbes, Ecsedy, Jeffrey, El‐Rifai, Wael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2017
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537695/
https://ncbi.nlm.nih.gov/pubmed/28417568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12066
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