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Rotavirus Genomic RNA Complex Forms via Specific RNA–RNA Interactions: Disruption of RNA Complex Inhibits Virus Infectivity

Rotavirus (RV), a member of the Reoviridae family, causes infection in children and infants, with high morbidity and mortality. To be viable, the virus particle must package a set of eleven RNA segments. In order to understand the packaging mechanism, here, we co-synthesized sets of RNA segments in...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Fajardo, Teodoro, Sung, Po-Yu, Celma, Cristina C., Roy, Polly
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537659/
https://ncbi.nlm.nih.gov/pubmed/28661470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v9070167
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