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Disruption of Specific RNA-RNA Interactions in a Double-Stranded RNA Virus Inhibits Genome Packaging and Virus Infectivity

Bluetongue virus (BTV) causes hemorrhagic disease in economically important livestock. The BTV genome is organized into ten discrete double-stranded RNA molecules (S1-S10) which have been suggested to follow a sequential packaging pathway from smallest to largest segment during virus capsid assembly...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Fajardo, Teodoro, Sung, Po-Yu, Roy, Polly
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672896/
https://ncbi.nlm.nih.gov/pubmed/26646790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005321
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