Nucleus accumbens-associated protein-1 promotes glycolysis and survival of hypoxic tumor cells via the HDAC4-HIF-1α axis

Nucleus accumbens-associated protein-1 (NAC1), a nuclear factor of the BTB/POZ gene family, has emerging roles in cancer. In this study, we identified the NAC1-HDAC4-HIF-1α axis as an important pathway in regulating glycolysis and hypoxic adaptation in tumor cells. We show that nuclear NAC1 binds to...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Oncogene
Main Authors: Zhang, Y, Ren, Y-J, Guo, L-C, Ji, C, Hu, J, Zhang, H-H, Xu, Q-H, Zhu, W-D, Ming, Z-J, Yuan, Y-S, Ren, X, Song, J, Yang, J-M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537617/
https://ncbi.nlm.nih.gov/pubmed/28319066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.51
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker