Characterisation of blood-derived exosomal hTERT mRNA secretion in cancer patients: a potential pan-cancer marker

BACKGROUND: Telomerase (human telomerase reverse transcriptase (hTERT)) is considered a hallmark of cancer. The aim of our study was to evaluate the feasibility of the detection of hTERT transcripts in serum as a ‘pan-cancer’ diagnostic method. METHODS: Human telomerase reverse transcriptase mRNA le...

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Detalles Bibliográficos
Publicado en:Br J Cancer
Main Authors: Goldvaser, Hadar, Gutkin, Anna, Beery, Einat, Edel, Yonatan, Nordenberg, Jardena, Wolach, Ofir, Rabizadeh, Ester, Uziel, Orit, Lahav, Meir
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
Assuntos:
Molecular Diagnostics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537487/
https://ncbi.nlm.nih.gov/pubmed/28641311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.166
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