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Shift of EMT gradient in 3D spheroid MSCs for activation of mesenchymal niche function
Despite the wide use of mesenchymal stromal cells (MSCs) for paracrine support in clinical trials, their variable and heterogeneous supporting activity pose major challenges. While three-dimensional (3D) MSC cultures are emerging as alternative approaches, key changes in cellular characteristics dur...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5537359/ https://ncbi.nlm.nih.gov/pubmed/28761088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07049-3 |
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