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Shift of EMT gradient in 3D spheroid MSCs for activation of mesenchymal niche function

Despite the wide use of mesenchymal stromal cells (MSCs) for paracrine support in clinical trials, their variable and heterogeneous supporting activity pose major challenges. While three-dimensional (3D) MSC cultures are emerging as alternative approaches, key changes in cellular characteristics dur...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jeon, Sohee, Lee, Ho-Sun, Lee, Ga-Young, Park, Gyeongsin, Kim, Tae-Min, Shin, Jihye, Lee, Cheolju, Oh, Il-Hoan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537359/
https://ncbi.nlm.nih.gov/pubmed/28761088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07049-3
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