Dynamics and mechanisms of clonal expansion of HIV-1-infected cells in a humanized mouse model

Combination anti-retroviral therapy (cART) has drastically improved the clinical outcome of HIV-1 infection. Nonetheless, despite effective cART, HIV-1 persists indefinitely in infected individuals. Clonal expansion of HIV-1-infected cells in peripheral blood has been reported recently. cART is effe...

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Publicado no:Sci Rep
Main Authors: Satou, Yorifumi, Katsuya, Hiroo, Fukuda, Asami, Misawa, Naoko, Ito, Jumpei, Uchiyama, Yoshikazu, Miyazato, Paola, Islam, Saiful, Fassati, Ariberto, Melamed, Anat, Bangham, Charles R. M., Koyanagi, Yoshio, Sato, Kei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537293/
https://ncbi.nlm.nih.gov/pubmed/28761140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07307-4
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