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Exendin-4 reduces food intake via the PI3K/AKT signaling pathway in the hypothalamus
Exendin-4 (EX-4), a glucagon-like peptide-1 (GLP-1) receptor agonist, has been shown to reduce food intake and to increase proopiomelanocortin (POMC) gene expression in the hypothalamus. In this study, we examined the potential neural mechanisms by which these effects occur. Male Sprague Dawley rats...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5537284/ https://ncbi.nlm.nih.gov/pubmed/28761132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06951-0 |
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