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Apolipoprotein E reduces food intake via PI3K/Akt signaling pathway in the hypothalamus
Apolipoprotein E (apoE) is a satiation factor. While central apoE administration reduces food intake, the specific intracellular signaling mechanisms activated by apoE remain largely unknown. Using primary cultured hypothalamic neurons, we demonstrated that apoE treatment (50 nM) elicited rapid acti...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3160520/ https://ncbi.nlm.nih.gov/pubmed/21536059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.physbeh.2011.04.018 |
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