Six Highly Conserved Targets of RNAi Revealed in HIV-1-Infected Patients from Russia Are Also Present in Many HIV-1 Strains Worldwide

RNAi has been suggested for use in gene therapy of HIV/AIDS, but the main problem is that HIV-1 is highly variable and could escape attack from the small interfering RNAs (siRNAs) due to even single nucleotide substitutions in the potential targets. To exhaustively check the variability in selected...

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Bibliographic Details
Published in:Mol Ther Nucleic Acids
Main Authors: Kretova, Olga V., Fedoseeva, Daria M., Gorbacheva, Maria A., Gashnikova, Natalya M., Gashnikova, Maria P., Melnikova, Nataliya V., Chechetkin, Vladimir R., Kravatsky, Yuri V., Tchurikov, Nickolai A.
Format: Artigo
Language:Inglês
Published: American Society of Gene & Cell Therapy 2017
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537207/
https://ncbi.nlm.nih.gov/pubmed/28918033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.07.010
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