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The human alpha 1-antitrypsin gene is transcribed from two different promoters in macrophages and hepatocytes.

In order to investigate the mechanism of expression of the human alpha 1-antitrypsin (alpha 1-AT) gene in macrophages, we have characterized the alpha 1-AT transcriptional units in these cells and discovered that there is a macrophage-specific promoter located approximately 2000 bp upstream of the h...

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Autori principali: Perlino, E, Cortese, R, Ciliberto, G
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1987
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC553701/
https://ncbi.nlm.nih.gov/pubmed/3500042
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