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Indoxyl sulfate, a uremic toxin in chronic kidney disease, suppresses both bone formation and bone resorption

Abnormalities of bone turnover are commonly observed in patients with chronic kidney disease (CKD), and the low‐turnover bone disease is considered to be associated with low serum parathyroid hormone (PTH) levels and skeletal resistance to PTH. Indoxyl sulfate (IS) is a representative uremic toxin t...

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Dades bibliogràfiques
Publicat a:FEBS Open Bio
Autors principals: Watanabe, Kenta, Tominari, Tsukasa, Hirata, Michiko, Matsumoto, Chiho, Hirata, Junya, Murphy, Gillian, Nagase, Hideaki, Miyaura, Chisato, Inada, Masaki
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536993/
https://ncbi.nlm.nih.gov/pubmed/28781957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12258
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